Roaccutane capsules contain isotretinoin. It belongs to a group of drugs which are derivatives of vitamin A. Roaccutane is an oral drug works by reducing the release of the skin’s natural oil also named as sebum.
Excessive production of natural oil from over-active sebaceous glands in the skin cause acne. The sebum blocks the sebaceous glands, which prevents the oil from flowing freely out and causes an accumulation of sebum under the skin. The bacteria associated with acne thrive in these conditions. They feed on the sebum, and produce waste products and fatty acids that irritate the sebaceous glands, making them inflamed and causing spots.
Roaccutane decreases the size and activity of the sebaceous glands in the skin, which means reduction on the amount of sebum that is produced. This stops the glands becoming blocked, and means bacteria are less likely to thrive. It also reduces the inflammation in the skin.
Isotretinoin can have serious side effects and its use must be supervised by a doctor. It is reserved for the treatment of severe acne (such as nodular or conglobate acne or acne at risk of permanent scarring) that has not improved with standard treatment involving oral antibiotics and topical medicines.
Your acne may worsen at the start of treatment, but this usually subsides within 7 to 10 days of continued treatment. In most cases, complete or near-complete clearing of acne is achieved with a 12 to 16 week course of treatment, and you are likely to remain free of acne for a long time. Repeat courses are not normally recommended, unless a definite relapse is seen after treatment is stopped. Repeat courses should not be started until at least eight weeks after stopping treatment, as your acne may still improve in this time.