American athletes have a long a fond relationship with Testosterone cypionate. While Testosterone enanthate is manufactured widely throughout the world, cypionate seems to be almost exclusively an American item. It is therefore not surprising that American athletes particularly favor this testosterone ester. But many claim this is not just a matter of simple pride, often swearing cypionate to be a superior product, providing a bit more of a “kick” than enanthate. At the same time it is said to produce a slightly higher level of water retention, but not enough for it to be easily discerned. Of course when we look at the situation objectively, we see these two steroids are really interchangeable, and cypionate is not at all superior. Both are long acting oil-based injectables, which will keep testosterone levels sufficiently elevated for approximately two weeks. Enanthate may be slightly better in terms of testosterone release, as this ester is one carbon atom lighter than cypionate (remember the ester is calculated in the steroids total milligram weight). The difference is so insignificant however that no one can rightly claim it to be noticeable (we are maybe talking a few milligrams per shot). Regardless, cypionate came to be the most popular testosterone ester on the U.S. black market for a very long time.
As with all testosterone injectables, one can expect a considerable gain in muscle mass and strength during a cycle. Since testosterone has a notably high affinity for estrogen conversion, the mass gained from this drug is likely to be accompanied by a discernible level of water retention. The resulting loss of definition of course makes cypionate a very poor choice for dieting or cutting phases. The excess level of estrogen brought about by this drug can also cause one to develop gynecomastia rather quickly. Should the user notice an uncomfortable soreness, swelling or lump under the nipple, an ancillary drug like Proviron® and/or Nolvadex® should probably be added. This will minimize the effect of estrogen greatly, making the steroid much more tolerable to use. The powerful antiaromatase Arimidex® is yet a better choice, but the high price tag prevents it from being more popularly used. Those who have a known sensitivity to estrogen may find it more beneficial to use ancillary drugs like Proviron® and Nolvadex® from the onset of the cycle, in order to prevent estrogen related side effects before they become apparent.